Canagen Collagen & Hyaluronic Acid Complex 500mg
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CANAGEN Biocell Collagen is the world’s first and only collagen product that has been proven in numerous human clinical trials and peer reviewed scientific studies to maintain healthy skin, reduce wrinkles and fine lines, tighten the skin, improve skin tone, improve hydration and create smooth and supple skin.

CANAGEN Biocell Collagen has also been proven in numerous clinical trials and peer reviewed scientific studies to help to relieve joint pain associated with osteoarthritis of the hip and knee and rebuild cartilage in the hip and knee joints.

CANAGEN Biocell Collagen is the world’s leading and most effective and technologically advanced collagen supplement and is the only collagen in the world that has been issued numerous global process and use patents for its unique, novel and advanced technology. (US Patent 6,025,327; 6,323,319; 6,780,841; 7,091,180; 7,799,348 other US and foreign patents pending) CANAGEN Biocell Collagen is therefore the world’s most scientifically researched, studied and clinically tested and proven collagen supplement, which confirms its highly superior effectiveness and safety.

CANAGEN Biocell Collagen is a multi-patented, hydrolyzed collagen-hyaluronic acid-chondroitin sulphate molecular matrix complex which replicates the human skin’s natural collagen-skin matrix. It contains all three of the most important molecules which make up the healthy human skin matrix and a highly advanced composition of hydrolyzed collagen type II, depolymerized chondroitin sulphate and bioavailable hyaluronic acid. It is derived from chicken sternum cartilage, nature’s richest source of collagen and hyaluronic acid, and is therefore highly bio-available to the human body. Numerous scientific studies conducted on CANAGEN Biocell Collagen confirm that it rapidly and effectively replenishes aging-related loss of collagen, hyaluronic acid and chondroitin sulphate in human skin, which are essential structural components of the skin.


For preventing the visible signs of skin aging, such as wrinkles and fine lines; for maintaining youthful skin appearance; for maintaining & improving youthful skin firmness, texture and elasticity; for prevention of wrinkles & fine lines & dehydration and scaling of skin. Helps to relieve joint pain associated with osteoarthritis of the hip and knee.


Clinically shown to improve joint comfort, mobility and quality of life.

Provides nutrients essential for maintaining cartilage, tendon and ligament connective tissue health.

Clinically shown to impact key biochemical markers of connective and skeletal muscle tissue damage and enhances stress resilience following intense resistance exercise.

The bio-available hyaluronic acid and chondroitin sulphate in CANAGEN Biocell Collagen promotes joint cushioning and lubrication.

May help renew cartilage by stimulating chondrocytes (cartilage producing cells)



Clinically shown to reduce fine lines and wrinkles by counteracting both natural and photo aging processes.

Clinically shown to reduce skin dryness/scaling via HA-mediated increase in skin hydration leading to enhanced turgidity and suppleness.

Clinically shown to increase collagen content in the dermis by supporting the tensile strength of skin.

Clinically shown to increase blood microcirculation of facial skin.

Promotes maintenance and healthy aging of skin.

Supports healthy hair and nails.



  • CANAGEN Biocell Collagen is registered, approved and licensed for sale by Health Canada and granted a natural health product number (NPN) by Health Canada. (NPN80064469) since April 2006


    CANAGEN Biocell Collagen is a fine, white powder and is encapsulated in 500 mg vegetable gelatin capsules. This product does not contain any hormones, preservatives, artificial colors or sweeteners. Each capsule contains 500 mg CANAGEN Biocell Collagen matrix compound, providing:

Hydrolyzed Collagen Type II Chondroitin Sulphate Hyaluronic Acid

300 mg 100 mg 50 mg


As an oral, highly bio-available, natural source of supplemental collagen, hyaluronic acid and chondroitin sulphate. Adults, pregnant or lactating women over 18 year of age should take 4 capsules daily (2 in the morning & 2 in the evening) or as directed by a physician. Benefits can be seen in one month


CANAGEN Biocell Collagen Does not have any known, demonstrable or reported contraindications. LABELLING

CANAGEN Biocell Collagen STORAGE

Store in a cool, dry environment away from direct sunlight. Rotation of stock is recommended


CANAGEN Biocell Collagen is packed in child resistant, tamper-proof bottles containing 30 x 500 mg capsules.



Unlike almost all producers of collagen, who use cheap fish skin or fish scale sources, CANAGEN Biocell Collagen is derived exclusively from chicken sterna cartilage, which is a rich source of collagen type II, hyaluronic acid and chondroitin sulfate and closely mirrors the composition of human articular cartilage. Cartilage is a very clean source because it is free from blood supply; it does not contain blood and lymphatic vessels or capillaries like other animal parts (e.g .hides, bones, skin and scales) which collagen types I & III are derived from. This is of importance because many bacteria, viruses, steroids, and antibiotics are carried through the blood supply. Collagen type II is rare and more valuable because it is predominantly found in cartilage where it naturally coexists with hyaluronic acid and chondroitin sulfate in a blood-free environment.

The ingestion of CANAGEN Biocell Collagen boosts the levels of all three collagen types (I, II, & III). BioCell Technologies published a human skin study on CANAGEN Biocell Collagen which showed that a daily intake of 1 gram of CANAGEN Biocell Collagen significantly reduced skin dryness and facial aging signs in association with an increase in blood circulation and collagen content (I/III) in the skin. This study, together with three human clinical trials of CANAGEN Biocell Collagen on joint health demonstrated that CANAGEN Biocell Collagen can support all major types (I, II and III) of collagen at a much lower daily dose than ‘generic’ hydrolyzed collagen (partial approach) lacking any hyaluronic acid and chondroitin.


At Canagen Pharmaceuticals Inc. we take the extra steps to make sure that our product is safe and effective for human consumption. That is why CANAGEN Biocell Collagen undergoes rigorous in- process, analytical, quality control testing during production and Quality Control (QC) testing and Quality Assurance (QA) review upon completion of every batch produced. CANAGEN Biocell Collagen is legally approved, registered and licensed by Health Canada’s Natural Health Products Directorate (NHPD). CANAGEN Biocell Collagen is manufactured via a multi-patented Bio-OptimizationTM procedure that includes filtration, purification, concentration, hydrolysis and sterilization, to ensure

consistent quality and safety. This multi-patented process removes impurities from the chicken sterna cartilage and remarkably reduces the size of all of its molecules, making them highly absorbable an dfast-acting. The composition and synergy among CANAGEN Biocell Collagen the three molecular constituents are unique and cannot be found in any other collagen ingredients or blends. CANAGEN Biocell Collagen is self-affirmed GRAS (Generally Recognized as Safe) with the U.S. FDA and gluten free. It offers a comprehensive approach to healthy aging by providing the nutritional building blocks of macromolecular collagen and GAGs essential for the proper structure and function of various connective tissues.


Aging produces many physiological and histological changes that affect how the body looks and feels. This depends, at least in part, upon the structural integrity of the connective tissue in joints, skin, tendons, ligaments, bones, and blood vessels. Connective tissue, which is primarily composed of collagen and glycosaminoglycans (GAGs), binds all of the organs and other tissues of the body. Aging gradually weakens the connective tissue by depleting the content of collagen and GAGs. There are many internal and external factors that physiologically influence the pace and effects of aging. The progression of aging is linked to steady deterioration of the extracellular matrix (ECM) in connective tissue, which results from decreased synthesis and increased degradation of molecules essential for connective tissue integrity. Since collagen and GAGs, such as chondroitin sulphate and hyaluronic acid (HA) are the major molecular constituents of the ECM, their replenishment could help counteract various undesirable effects of aging. These effects include overall bodily weakness, vulnerability to injury, and visible facial changes. CANAGEN Biocell Collagen comprehensively addresses the loss of these molecules by providing both collagen and GAGs, and its safety, efficacy and bioavailability have been substantiated by numerous, peer-reviewed human clinical trials and studies. Multiple human clinical studies, including safety, efficacy, and bioavailability trials have demonstrated that CANAGEN Biocell Collagen is an essential healthy anti-aging ingredient that promotes joint health and skin beauty. CANAGEN Biocell Collagen is a multifaceted healthy aging dietary ingredient that contains a patented composition of naturally occurring hydrolyzed collagen type II (70%), chondroitin sulfate (20%) and hyaluronic acid (10%) in a highly absorbable and bio-available matrix form (NOT A BLEND). This unique product technology helps the body to rebuild collagen and skin matrix from within and also helps stimulate the body’s production of collagen.


Suggested Use

Take 2 capsules daily, preferably 20 minutes before a meal or as directed by your health practitioner.

Use for 12 weeks to see beneficial effects.

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